Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans
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چکیده
منابع مشابه
Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans
Circular RNAs (circRNAs) are broadly expressed in eukaryotic cells, but their molecular mechanism in human disease remains obscure. Here we show that circular antisense non-coding RNA in the INK4 locus (circANRIL), which is transcribed at a locus of atherosclerotic cardiovascular disease on chromosome 9p21, confers atheroprotection by controlling ribosomal RNA (rRNA) maturation and modulating p...
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ژورنال
عنوان ژورنال: Nature Communications
سال: 2016
ISSN: 2041-1723
DOI: 10.1038/ncomms12429